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Moreover, effective delivery of therapeutic drugs to the joint site following systemic administration remains highly challenging, severely limiting their clinical efficacy

Geusens PP, Boonen S: Osteoporosis and the growth hormone-insulin like growth factor axis

Obesity Research & Clinical Practice, 9(3), 301-304

What it cannot yet tell us is whether managing those risks successfully translates into the broader healthspan outcomes this article has been building toward: preserved cognitive function, durable cardiovascular resilience, sustained lean mass, and reduced long-term disease burden

Looking forward to surgery